王一男 讲师,博士,硕士生导师 |
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科学研究方向 |
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药物分析及药物与蛋白靶点互作 |
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联系方式 |
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电 话:0516-83262138 |
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Email:sddxwyn@163.com |
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通 讯:江苏省徐州市云龙区铜山路209号,221004 |
个人简历
王一男,男,hg8868官网,药物分析教研室讲师。1989年5月生。2011年本科毕业于山东大学药学专业;2014年毕业于沈阳药科大学药物分析学专业,获得理学硕士学位;2017年毕业于沈阳药科大学药物分析学专业,获得理学博士学位。研究方向为中药药效物质基础、药物分子与蛋白靶点互作。以第一作者发表SCI论文7篇,主持徐州市课题一项。担任药物分析及分析化学课程的理论及实践教学工作。
承担科研课题
1. 徐州市科技计划项目,KC18054, 基于质谱成像和SWATH-MS技术的高尿酸血症及其肾病的生物标志物发现研究,2018.11-2020.10,5万元,主持。
2. 徐州医科大学优博人才项目,53681723,秦皮治疗高尿酸血症的药效物质基础和作用机制研究,2018.07-2021.06,30万元,主持。
3. 国家自然科学基金青年基金,81803382,基于功能化离子液体靶向富集的甘草中异戊烯基黄酮的制备分离及其诱导自噬构效关系研究,2019.01-2021.12,21万元,参与。
近五年代表性论文、专著
1. Yinan Wang#, Youhui Hu#, Hui Wang, Minghui Tong, Yinhan Gong*. Green and enhanced extraction of coumarins from Cortex Fraxini by ultrasound-assisted deep eutectic solvent extraction . Journal of Separation Science, 2020, 43: 3441-3448.(IF=2.878)
2. Yinan Wang, Min Zhao#, Hao Ye, Yizhen Shao, Yongbo Yu, Miao Wang*, Chunjie Zhao*. Comparative pharmacokinetic study of the main components of Cortex Fraxini after oral administration in normal and hyperuricemic rats. Biomedical Chromatography, 2017, 31: e3934. (IF= 1.728)
3. Yinan Wang, Min Zhao, Yi Xin, Jiajia Liu, MiaoWang*, Chunjie Zhao*. 1H-NMR and MS based metabolomics study of the therapeutic effect of Cortex Fraxini on hyperuricemic rats. Journal of Ethnopharmacology, 2016, 185: 272–281.(IF= 3.690)
4. Yinan Wang, Min Zhao, Yingfu Ou, Bowen Zeng, Xinyu Lou, Miao Wang*, Chunjie Zhao*. Metabolic profile of esculin in rats by ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry. Journal of Chromatography B, 2016, 1020: 120–128. (IF= 3.004)
5. Yinan Wang, Min Zhao, Yongbo Yu, Miao Wang*, Chunjie Zhao*. Metabolic profile of Cortex Fraxini in rats using UHPLC combined with Fourier transform ion cyclotron resonance mass spectrometry. RSC Advances, 2016, 6: 39642–39651. (IF= 3.119)
6. Yinan Wang, Fei Han, Aihua Song, Miao Wang, Min Zhao*, Chunjie Zhao*. Rapid characterization of the chemical constituents of Cortex Fraxini by homogenate extraction followed by UHPLC coupled with Fourier transform ion cyclotron resonance mass spectrometry and GC–MS. Journal of Separation Science, 2016, 39: 4325–4334. (IF=2.878)
7. Yinan Wang#, Min Zhao#, Miao Wang*, Chunjie Zhao*. Profiling analysis of amino acids from hyperlipidaemic rats treated with Gynostemma pentaphyllum and atorvastatin. Pharmaceutical Biology, 2016, 54: 2254–2263. (IF= 2.971)